Number of reported cases of tuberculosis (DOTS) (number)
| 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 |
| Guatemala | 2,913 | 3,803 | 3,322 | 3,040 | 3,442 | 3,311 | 3,163 | 3,325 | 3,223 | 3,445 | 3,568 | 3,716 | 2,750 | 3,089 | 4,092 | 4,733 |
| Saint Vincent and the Grenadines | 16 | 7 | 15 | 17 | 30 | 3 | 5 | 7 | 6 | 2 | 6 | 4 | 13 | 5 | 5 | 4 |
| Barbados | 3 | | 6 | 0 | 4 | 4 | 5 | 0 | 3 | 0 | 1 | 0 | 6 | 1 | 5 | 2 |
| Saint Kitts and Nevis | 0 | 0 | 2 | 1 | 2 | 0 | 7 | | 0 | 1 | 0 | 2 | 2 | 0 | | 1 |
| Jamaica | 127 | 90 | 130 | 105 | 91 | 96 | 86 | 103 | 103 | 121 | 82 | 75 | 61 | 57 | 83 | 83 |
| Dominican Republic | 5,291 | 5,003 | 3,964 | 4,309 | 4,262 | 4,450 | 4,405 | 4,504 | 4,235 | 3,851 | 3,857 | 3,588 | 2,619 | 3,374 | 4,080 | 4,377 |
| Venezuela (Bolivarian Republic of) | 6,466 | 6,847 | 6,451 | 6,282 | 6,495 | 6,555 | 6,392 | 7,136 | 8,197 | 10,647 | 11,017 | 10,293 | 9,150 | 9,090 | 9,865 | 10,165 |
| Trinidad and Tobago | 198 | 166 | 219 | 224 | 274 | 250 | 251 | 196 | 214 | 200 | 253 | 218 | 220 | 171 | 243 | 277 |
| Panama | 1,169 | 1,637 | 1,541 | 1,632 | 1,520 | 1,449 | 1,457 | 1,646 | 1,810 | 1,874 | 1,723 | 1,265 | 1,133 | 1,452 | 1,645 | 2,077 |
| Saint Lucia | 9 | 14 | 9 | 7 | 11 | 9 | 6 | 14 | 3 | 11 | 5 | 6 | 8 | 4 | 2 | 2 |
| Guyana | 422 | 639 | 712 | 710 | 748 | 679 | 545 | 571 | 577 | 524 | 516 | 497 | 366 | 414 | 390 | 424 |
| Haiti | 10,420 | 14,311 | 14,222 | 15,225 | 16,571 | 17,040 | 15,806 | 16,234 | 15,302 | 14,966 | 13,383 | 13,019 | 11,273 | 10,407 | 11,138 | 11,714 |
| Colombia | 11,630 | 10,360 | 11,420 | 11,884 | 12,097 | 11,737 | 11,637 | 11,858 | 12,581 | 13,007 | 13,140 | 14,292 | 12,088 | 13,659 | 16,692 | 19,970 |
| Bahamas | 82 | 48 | 31 | 41 | 32 | 33 | 50 | 62 | 89 | 51 | 47 | 51 | 31 | 44 | 48 | 27 |
| Dominica | | | 8 | 2 | 7 | 3 | 1 | 7 | 5 | 1 | 4 | 10 | | 0 | 0 | 4 |
| El Salvador | 1,485 | 1,794 | 1,700 | 1,896 | 2,053 | 2,176 | 2,206 | 2,452 | 3,034 | 3,666 | 3,615 | 3,009 | 2,042 | 1,936 | 2,531 | 4,265 |
| Belize | 106 | 102 | 145 | 74 | 84 | 121 | 72 | 78 | 120 | 117 | 99 | 91 | 78 | 72 | 75 | 81 |
| Mexico | 18,434 | 18,524 | 20,155 | 19,857 | 20,470 | 20,708 | 21,196 | 21,600 | 22,193 | 22,757 | 23,271 | 23,702 | 17,603 | 21,651 | 25,449 | 27,030 |
| Honduras | 6,406 | 3,333 | 2,876 | 3,233 | 3,014 | 2,981 | 2,789 | 2,906 | 2,886 | 2,798 | 2,838 | 2,424 | 1,847 | 2,063 | 2,297 | 2,616 |
| Suriname | 89 | 117 | 194 | 125 | 128 | 141 | 146 | 144 | 114 | 129 | 174 | 133 | 103 | 88 | 124 | 120 |
| Cuba | 1,183 | 772 | 827 | 805 | 734 | 757 | 729 | 698 | 682 | 712 | 710 | 636 | 580 | 509 | 717 | 753 |
| Nicaragua | 2,402 | 1,907 | 2,448 | 2,693 | 2,790 | 2,742 | 2,632 | 2,465 | 2,339 | 2,255 | 2,109 | 2,248 | 1,886 | 1,836 | 2,102 | 2,122 |
| Grenada | 0 | | 4 | 2 | 1 | | 0 | 5 | 6 | 3 | 2 | 3 | 1 | 2 | 1 | 5 |
| Costa Rica | 585 | 534 | 492 | 514 | 475 | 410 | 463 | 424 | 368 | 379 | 401 | 405 | 342 | 350 | 392 | 474 |
| Antigua and Barbuda | 4 | 6 | 7 | 6 | 3 | 10 | 3 | | 3 | 1 | 5 | 0 | 2 | 4 | 1 | 1 |