Number of reported cases of tuberculosis (DOTS) (number)
| 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 |
| Kenya | 64,159 | 102,680 | 99,272 | 97,320 | 92,987 | 89,796 | 88,025 | 81,292 | 76,335 | 83,599 | 94,534 | 84,345 | 71,060 | 76,010 | 88,690 | 94,653 |
| South Sudan | | | | 7,217 | 8,403 | 6,422 | 8,335 | 9,657 | 10,770 | 10,220 | 14,603 | 16,323 | 15,969 | 17,468 | 19,659 | 23,918 |
| Uganda | 30,372 | 41,040 | 42,885 | 46,306 | 44,663 | 45,549 | 44,187 | 41,912 | 43,413 | 45,794 | 55,835 | 65,897 | 60,887 | 74,799 | 94,457 | 86,469 |
| Rwanda | 6,093 | 7,220 | 6,703 | 6,623 | 6,091 | 5,702 | 5,761 | 5,534 | 5,792 | 5,593 | 5,822 | 5,766 | 5,511 | 5,216 | 6,986 | 9,335 |
| Burundi | 6,421 | 6,585 | 7,611 | 6,742 | 6,921 | 7,467 | 7,226 | 6,892 | 7,567 | 7,760 | 7,202 | 6,753 | 7,105 | 6,788 | 7,587 | 7,948 |
| United Republic of Tanzania | 54,442 | 61,022 | 61,098 | 59,357 | 62,479 | 64,053 | 61,571 | 60,895 | 64,609 | 68,273 | 74,692 | 81,208 | 84,791 | 86,701 | 100,100 | 92,368 |