Neonatal mortality rate is the number of neonates dying before reaching 28 days of age, per 1,000 live births in a given year.
| 1970 | 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Belize | 34.3 | 18.7 | 12.1 | 10.1 | 10.4 | 10.8 | 11.0 | 10.9 | 10.8 | 10.5 | 10.2 | 9.9 | 9.7 | 9.6 | 9.5 | 9.4 | 9.4 | 9.3 |
| Costa Rica | 26.1 | 8.9 | 7.6 | 7.1 | 6.6 | 6.5 | 6.4 | 6.3 | 6.3 | 6.2 | 6.1 | 6.1 | 6.2 | 6.2 | 6.4 | 6.6 | 6.9 | 7.2 |
| Dominican Republic | 40.2 | 24.4 | 23.0 | 23.1 | 24.0 | 24.1 | 24.2 | 24.2 | 24.3 | 24.3 | 24.4 | 24.3 | 24.1 | 23.8 | 23.4 | 22.9 | 22.3 | 21.7 |
| El Salvador | 22.5 | 14.5 | 10.8 | 8.2 | 7.8 | 7.4 | 7.0 | 6.7 | 6.3 | 6.0 | 5.7 | 5.4 | 5.2 | 5.0 | 4.8 | 4.6 | 4.4 | |
| Guatemala | 51.6 | 28.2 | 21.3 | 18.6 | 16.2 | 15.5 | 15.0 | 14.4 | 13.8 | 13.3 | 12.8 | 12.3 | 11.9 | 11.5 | 11.1 | 10.7 | 10.4 | 10.0 |
| Honduras | 21.7 | 17.9 | 15.6 | 13.9 | 13.5 | 13.0 | 12.6 | 12.2 | 11.7 | 11.3 | 10.9 | 10.5 | 10.1 | 9.8 | 9.5 | 9.1 | 8.8 | |
| Nicaragua | 22.8 | 16.6 | 13.8 | 12.5 | 12.3 | 12.0 | 11.7 | 11.3 | 10.9 | 10.4 | 10.0 | 9.8 | 9.6 | 9.6 | 9.3 | 8.9 | 8.4 | |
| Panama | 31.9 | 15.6 | 12.2 | 9.9 | 8.1 | 7.9 | 7.6 | 7.5 | 7.4 | 7.4 | 7.4 | 7.5 | 7.6 | 7.5 | 7.4 | 7.1 | 6.9 | 6.6 |