Prevalence of HIV is the percentage of people who are infected with HIV. Female rate is as a percentage of the total population with HIV.
| 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dominican Republic | 59.6 | 50.9 | 49.7 | 50.1 | 50.3 | 50.6 | 50.8 | 51.0 | 51.1 | 51.2 | 51.2 | 51.2 | 51.2 | 51.2 | 51.1 | 51.0 | 51.0 | 50.9 |
| Belize | 37.1 | 40.1 | 41.3 | 42.9 | 43.3 | 43.7 | 44.1 | 44.4 | 44.7 | 44.9 | 45.2 | 45.5 | 45.8 | 46.1 | 46.4 | 46.4 | 46.5 | 46.6 |
| Honduras | 50.2 | 45.5 | 43.8 | 44.3 | 44.4 | 44.5 | 44.6 | 44.8 | 44.8 | 44.7 | 44.5 | 44.1 | 43.7 | 43.3 | 42.7 | 42.2 | 41.7 | 41.2 |
| Guatemala | 47.2 | 44.0 | 41.4 | 38.8 | 38.6 | 38.5 | 38.4 | 38.4 | 38.4 | 38.3 | 38.2 | 38.0 | 37.7 | 37.4 | 37.0 | 36.7 | 36.4 | 36.1 |
| El Salvador | 29.9 | 30.2 | 31.2 | 32.1 | 32.3 | 32.6 | 33.1 | 33.5 | 34.0 | 34.3 | 34.7 | 35.1 | 35.3 | 35.3 | 35.2 | 35.1 | 34.9 | 34.7 |
| Nicaragua | 52.2 | 37.4 | 36.0 | 34.3 | 34.1 | 33.9 | 33.7 | 33.6 | 33.6 | 33.4 | 33.2 | 33.0 | 32.8 | 32.6 | 32.2 | 31.8 | 31.5 | 31.2 |
| Panama | 25.4 | 27.8 | 28.9 | 29.5 | 29.6 | 29.6 | 29.6 | 29.6 | 29.6 | 29.6 | 29.7 | 29.7 | 29.5 | 29.2 | 28.9 | 28.7 | 28.5 | 28.4 |
| Costa Rica | 23.3 | 21.1 | 19.9 | 18.8 | 18.4 | 18.0 | 17.7 | 17.3 | 16.9 | 16.6 | 16.3 | 16.0 | 15.7 | 15.3 | 15.0 | 14.8 | 14.6 | 14.4 |