Patent applications are worldwide patent applications filed through the Patent Cooperation Treaty procedure or with a national patent office.
| 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Belize | 33 | 49 | 51 | 32 | 36 | 26 | 37 | 32 | 24 | 32 | 23 | 27 | |||
| Costa Rica | 43 | 47 | 423 | 606 | 610 | 578 | 580 | 529 | 582 | 497 | 504 | 490 | 483 | 524 | 566 |
| Dominican Republic | 63 | 217 | 328 | 318 | 265 | 256 | 244 | 227 | 242 | 251 | 211 | 220 | 207 | 220 | |
| El Salvador | 44 | 217 | 183 | 187 | 196 | 171 | 178 | 136 | 147 | 143 | 144 | ||||
| Guatemala | 97 | 250 | 388 | 374 | 327 | 337 | 319 | 288 | 341 | 266 | 275 | 228 | 231 | 205 | 249 |
| Honduras | 17 | 135 | 253 | 233 | 211 | 224 | 185 | 189 | 148 | 187 | 188 | ||||
| Nicaragua | 129 | 208 | 172 | 124 | 145 | ||||||||||
| Panama | 53 | 153 | 468 | 420 | 234 | 78 | 274 | 389 | 349 | 376 | 362 | 328 | 297 | 401 |