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Managua is the top region by influenza in Nicaragua. As of 2011, influenza in Managua was 30,560 that accounts for 37.32 % of Nicaragua's influenza. The top 5 regions (others are León, Chinandega, Nueva Segovia, and Carazo) account for 68.72 % of it. Nicaragua's total influenza was estimated at 81,895 in 2011.

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