Montevideo is the top region by population in Uruguay. As of 2016, population in Montevideo was 1.38 million persons that accounts for 39.67% of Uruguay's population. The top 5 regions (others are Canelones, Maldonado, Salto, and Colonia) account for 68.99% of it. Uruguay's total population was estimated at 3.48 million persons in 2016.

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The table includes 437 people homeless and 34,223 people estimated in homes with absent residents.